Submit a drug–adverse-event claim
Inputs hashed and pre-registration sha1-locked at submission. The pipeline runs and publishes a signed verdict — positive or null.
Discover mode — scan a single drug
Submit just a drug name. The engine enumerates the top 20 adverse events, validates each, and ranks the survivors by PRR.
Drug-class scans
Eleven curated classes — SGLT2 inhibitors, GLP-1 agonists, anti-amyloid mAbs, KRAS G12C, BTK inhibitors, S1P modulators, CGRP antagonists, and more. Fan out across every member drug.
Gates that must clear
Dedup ≥ 5 unique cases · suspect-drug filter · max co-exposure < 80% · PRR ≥ 2 with lower 95% CI > 1 · n ≥ 3.
Status, not score
Findings publish as candidate, then are promoted to audit-grade after operator review, or retired to null-result / withdrawn.
Browser-verifiable signatures
Each finding has a public verify page. Paste the identifier, see the evidence hash, prior-entry chain link, and Ed25519 signature. No login. No install.
Signed audit packets
Every finding ships as a downloadable tar.gz with the manifest, the canonical bundle, the rendered HTML fragment, and step-by-step verify instructions.
Honest null results
Findings that don't clear the gates are signed and published anyway — proof the platform doesn't bury what doesn't validate.
Validate post-market drug-safety claims with the same disproportionality math regulators use — pre-registered, signed, falsifiable
For real-world evidence teams, pharmacoepidemiology groups, signal-detection scientists, clinical-pharmacology directors, biotech R&D teams. Submit single drug+AE claims, run single-drug discovery scans, or run drug-class scans across curated cohorts. Every verdict cryptographically signed and browser-verifiable.
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